EU project for the development of a versatile biosensing platform with ultra-rapid detection

The development of innovative biosensor platforms characterized by a rapid and highly sensitive detection as well as versatile application are of critical importance for various areas from medical diagnostics and food monitoring to environmental analyses.

The project DeDNAed, funded by the European Union within the framework of Horizon 2020, aims at the development of such a biosensing platform with ultrarapid optical detection. DNA origami is used for the assembly of transducer and the so-called biological recognition element (here DNA or antibodies) controlling the sensor architecture on the nanometer scale. Analyte binding will be detected by surface-enhanced Raman spectroscopy with the signal being further enhanced by arranging multiple recognition elements within a nanoarray. This technology is not limited to a certain biomarker thus enabling the development of sensors for a wide range of applications. Additionally, the combination of this sensing technology with flexible surfaces will be tested. In this project our group focusses on microtiter plate-based analyses as well as kinetic measurements for system validation.

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Aside from University Potsdam, the following European institutions participate in the realization of this project which is coordinated by the Technical University Chemnitz: Asociacion Centro De Investigacion Cooperativa En Biomateriales (CIC biomaGUNE, San Sebastian, Spain), Kurt-Schwabe-Institute für Mess- und Sensortechnik e.V. Meinsberg (Waldheim, Germany), Université du Mans (Le Mans, France), Fundacion Tecnalia Research & Innovation (San Sebastian, Spain), and the Bionanonet Forschungsgesellschaft mbH (Graz, Austria).

For more information visit the project website.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 964248.

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