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Static and dynamic light scattering
In SLS and DLS experiments we analyze the scattering of laser light by peptide solutions. The mean scattering intensity of the peptide solutions relative to a scattering standard solution is used to determine the molecular mass of the peptide in solution (SLS). In contrast, from the time dependent fluctuation of the scattering signal the diffusion coefficient of the peptide can be calculated (DLS). Combining both methods changes in the peptide association state can be analyzed, e.g. during aggregation.
We have several custom-made light scattering apparatuses which we are constantly developing further.