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Prof. Dr. med. Dr. phil. Michael Rapp


Campus Golm
House 62, Room 2.07 (H-Lab)

Am Mühlenberg 9
14476 Potsdam


consulting hours
During semester:
Mondays 13.00-14.00 Uhr
Registration via Email is required!

Prof. Dr. med. Dr. phil. Michael Rapp

Office hours during the semester:
Mondays 13.00-14.00
Registration via email required!


Scientific focus

  • plasticity in old age
  • prevention of mental disorders across the lifespan
Prof. Dr. med. Dr. phil. Michael Rapp


Campus Golm
House 62, Room 2.07 (H-Lab)

Am Mühlenberg 9
14476 Potsdam


consulting hours
During semester:
Mondays 13.00-14.00 Uhr
Registration via Email is required!

publications (selection)


Förstner, B. R., Tschorn, M., Reinoso-Schiller, N., Maričić, L. M., Roecher, E., Kalman, J. L., ... & Rapp, M. A. (2023). Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis. European Archives of Psychiatry and Clinical Neuroscience, 273(3), 527-539.


Böge, K., Karnouk, C., Hoell, A., Tschorn, M., Kamp-Becker, I., Padberg, F., Übleis, A., Hasan, A., Falkai, P., Salize, H.-J., & others. (2022). Effectiveness and cost-effectiveness for the treatment of depressive symptoms in refugees and asylum seekers: A multi-centred randomized controlled trial. The Lancet Regional Health-Europe, 19, 100413.

Deeken, F., & Rapp, M. (2022). Technology-based interventions as an approach to treating apathy in people with dementia. International Psychogeriatrics, 34(2), 95–96.

Deeken, F., Sánchez, A., Rapp, M. A., Denkinger, M., Brefka, S., Spank, J., Bruns, C., von Arnim, C. A. F., Kuster, O. C., & Conz..., L. O. (2022). Outcomes of a Delirium Prevention Program in Older Persons After Elective Surgery. JAMA Surgery, 157(2), e216370.

Garbusow, M., Ebrahimi, C., Riemerschmid, C., Daldrup, L., Rothkirch, M., Chen, K., Chen, H., Belanger, M. J., Hentschel, A., Smolka, M. N., Heinz, A., Pilhatsch, M., & Rapp, M. A. (2022). Pavlovian-to-Instrumental Transfer across Mental Disorders: A Review. Neuropsychobiology, 120.

Heinzel, S., Schwefel, M., Sanchez, A., Heinen, D., Fehm, L., Henze, R., Teran, C., Kallies, G., Rapp, M. A., Fydrich, T., Strohle, A., & Heissel, A. (2022). Physical exercise training as preceding treatment to cognitive behavioral therapy in mild to moderate major depressive disorder: A randomized controlled trial. Journal of Affective Disorders, 319, 9098.

Hoffmann, S., Tschorn, M., Michalski, N., Hoebel, J., Forstner, B. R., Rapp, M. A., & Spallek, J. (2022). Association of regional socioeconomic deprivation and rurality with global developmental delay in early childhood: Data from mandatory school entry examinations in Germany. Health & Place, 75, 102794.

Mueckstein, M., Heinzel, S., Granacher, U., Brahms, M., Rapp, M. A., & Stelzel, C. (2022). Modality-specific effects of mental fatigue in multitasking. Acta Psychologica, 230, 103766.

Tschorn, M., Schulze, S., Forstner, B. R., Holmberg, C., Spallek, J., Heinz, A., & Rapp, M. A. (2022). Predictors and prevalence of hazardous alcohol use in middle-late to late adulthood in Europe. Aging & Mental Health, 110.


Chen, H., Mojtahedzadeh, N., Belanger, M. J., Nebe, S., Kuitunen-Paul, S., Sebold, M., Garbusow, M., Huys, Q. J. M., Heinz, A., Rapp, M. A., & Smolka, M. N. (2021). Model-Based and Model-Free Control Predicts Alcohol Consumption Developmental Trajectory in Young Adults: A 3-Year Prospective Study. Biological Psychiatry, 89(10), 980989.

Eschweiler, G. W., Czornik, M., Herrmann, M. L., Knauer, Y. P., Forkavets, O., von Arnim, C. A. F., Denkinger, M., Kuster, O., Conzelmann, L., Metz, B. R., Maurer, C., Kentischer, F., Deeken, F., Sanchez, A., Wagner, S., Mennig, E., Thomas, C., & Rapp, M. A. (2021). Presurgical Screening Improves Risk Prediction for Delirium in Elective Surgery of Older Patients: The PAWEL RISK Study. Frontiers in Aging Neuroscience, 13, 679933.

Rezo, A., Brunnhuber, S., Gil, F. P., Fernandez, A. C. S., & Rapp, M. A. (2021). Integrative medicine for mental health (INTEGRAL)-An ongoing health service research project comparing psychiatric routine care and integrative psychiatry. European Journal of Integrative Medicine, 48, 102014.

Schumann, G., Tschorn, M., Heinz, A., & Rapp, M. (2021). Jenseits von IMAGEN: populationsneurowissenschaftliche Strategien für klinische und globale Kohorten in den STRATIFY-und GIGA-Konsortien. Der Nervenarzt, 92(3), 234–242.

Tschorn, M., Lorenz, R. C., O’Reilly, P. F., Reichenberg, A., Banaschewski, T., Bokde, A. L., ... & Rapp, M. A. (2021). Differential predictors for alcohol use in adolescents as a function of familial risk. Translational psychiatry, 11(1), 157.


Boge, K., Karnouk, C., Hahn, E., Schneider, F., Habel, U., Banaschewski, T., Meyer-Lindenberg, A., Salize, H. J., Kamp-Becker, I., Padberg, F., Hasan, A., Falkai, P., Rapp, M. A., Plener, P. L., Stamm, T., Elnahrawy, N., Lieb, K., Heinz, A., & Bajbouj, M. (2020). Mental health in refugees and asylum seekers (MEHIRA): study design and methodology of a prospective multicentre randomized controlled trail investigating the effects of a stepped and collaborative care model. European Archives of Psychiatry and Clinical Neuroscience, 270(1), 95106.

Deeken, F., Banaschewski, T., Kluge, U., & Rapp, M. A. (2020). Risk and protective factors for alcohol use disorders across the lifespan. Current Addiction Reports, 7(3), 245–251.

Heissel, A., Pietrek, A., Schwefel, M., Abula, K., Wilbertz, G., Heinzel, S., & Rapp, M. (2020). STEP.De study -a multicentre cluster-randomised effectiveness trial of exercise therapy for patients with depressive symptoms in healthcare services: study protocol. BMJ Open, 10(4), Article 4.

Houtenbos, S. P., Schraplau, A., Rapp, M. A., Wippert, P.-M., Völler, H., Bonaventura, K., & Mayer, F. (2020). Reliability And Validity Of A Mobile Setup For Metabolic Syndrome Diagnosis Using Point-of-care Analyzers: 3915 Board# 232 May 30 9: 00 AM-10: 30 AM. Medicine & Science in Sports & Exercise, 52(7S), 1078–1079.

Schad, D. J., Rapp, M. A., Garbusow, M., Nebe, S., Sebold, M., Obst, E., Sommer, C., Deserno, L., Rabovsky, M., Friedel, E., Romanczuk-Seiferth, N., Wittchen, H.-U., Zimmermann, U. S., Walter, H., Sterzer, P., Smolka, M. N., Schlagenhauf, F., Heinz, A., Dayan, P., & Huys, Q. J. M. (2020). Dissociating neural learning signals in human sign- and goal-trackers. Nature Human Behaviour, 4(2), 201214.

Zech, P., Schuch, F., Pérez-Chaparro, C., Kangas, M., Rapp, M., & Heissel, A. (2020). Exercise, comorbidities, and health-related quality of life in people living with HIV: The HIBES cohort study. International Journal of Environmental Research and Public Health, 17(14), 5138.


Schad, D. J., Rapp, M. A., Garbusow, M., Nebe, S., Sebold, M., Obst, E., ... & Romanczuk-Seiferth, N. (2019). Dissociating neural learning signals in human sign-and goal-trackers. Nature human behaviour, 1-14.

Deeken, F., Rezo, A., Hinz, M., Discher, R., & Rapp, M. A. (2019). Evaluation of Technology-Based Interventions for Informal Caregivers of Patients With Dementia—A Meta-Analysis of Randomized Controlled Trials. The American Journal of Geriatric Psychiatry27(4), 426-445.

Schad, D. J., Garbusow, M., Friedel, E., Sommer, C., Sebold, M., Hägele, C., ... & Rapp, M. A. (2019). Neural correlates of instrumental responding in the context of alcohol-related cues index disorder severity and relapse risk. European archives of psychiatry and clinical neuroscience269(3), 295-308.

Sánchez, A., Thomas, C., Deeken, F., Wagner, S., Klöppel, S., Kentischer, F., ... & Rapp, M. A.. (2019). Patient safety, cost-effectiveness, and quality of life: reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults—study protocol for a stepped-wedge cluster randomized trial (PAWEL Study). Trials20(1), 71.

Heissel, A., Pietrek, A., Rapp, M. A., Heinzel, S., & Williams, G. (2019). Perceived Health Care Climate of Older People Attending an Exercise Program: Validation of the German Short Version of the Health Care Climate Questionnaire. Journal of aging and physical activity1(aop), 1-11.


Gellert, P., Häusler, A., Suhr, R., Gholami, M., Rapp, M., Kuhlmey, A., & Nordheim, J. (2018). Testing the stress-buffering hypothesis of social support in couples coping with early-stage dementia. PloS One13(1), e0189849.

Schad, D. J., Garbusow, M., Friedel, E., Sommer, C., Sebold, M., Hägele, C., …Rapp, M. A. (2018). Neural correlates of instrumental responding in the context of alcohol-related cues index disorder severity and relapse risk. European Archives of Psychiatry and Clinical Neuroscience

Deeken, F., Häusler, A., Nordheim, J., Rapp, M., Knoll, N., & Rieckmann, N. (2018). Psychometric properties of the Perceived Stress Scale in a sample of German dementia patients and their caregivers. International Psychogeriatrics30(1), 39–47.


Gruebner, O., A. Rapp, M., Adli, M., Kluge, U., Galea, S., & Heinz, A. (2017). Cities and Mental Health. Deutsches Ärzteblatt International114(8), 121–127.

Gutzmann, H., & Rapp, M. (2017). Systematik organisch-symptomatischer Störungen. In H. J. Möller, G. Laux, & H. P. Kapfhammer (Hrsg.), Psychiatrie, Psychosomatik, Psychotherapie (S. 1351–1364). Springer, Berlin, Heidelberg.

Heinzel, S., Lorenz, R. C., Duong, Q.-L., Rapp, M. A., & Deserno, L. (2017). Prefrontal-parietal effective connectivity during working memory in older adults. Neurobiology of Aging57, 18–27.

Heinzel, S., Rapp, M. A., Fydrich, T., Ströhle, A., Terán, C., Kallies, G., … Heissel, A. (2018). Neurobiological mechanisms of exercise and psychotherapy in depression: The SPeED study-Rationale, design, and methodological issues. Clinical Trials (London, England)15(1), 53–64.

Rapp, M. A., Tschorn, M., Sebold, M., Garbusow, M., Smolka, M., & Heinz, A. (2017). Multivariate Prädiktion von Trinkverhalten: Das Ganze ist weniger als die Summe seiner Teile. In Suchttherapie (Bd. 18, S. S-11-04-11). Georg Thieme Verlag KG.

Sebold, M., Nebe, S., Garbusow, M., Guggenmos, M., Schad, D. J., Beck, A., … Heinz, A. (2017). When Habits Are Dangerous: Alcohol Expectancies and Habitual Decision Making Predict Relapse in Alcohol Dependence. Biological Psychiatry82(11), 847–856.

Stelzel, C., Schauenburg, G., Rapp, M. A., Heinzel, S., & Granacher, U. (2017). Age-Related Interference between the Selection of Input-Output Modality Mappings and Postural Control-a Pilot Study. Frontiers in Psychology8, 613.


Bauer, M., Banaschewski, T., Heinz, A., Kamp-Becker, I., Meyer-Lindenberg, A., Padberg, F.,. . . Wittchen, H. (2016). Das deutsche Forschungsnetz zu psychischen Erkrankungen. Der Nervenarzt, 87(9), 989–1010. 

Booker, A., Jacob, L. E. C., Rapp, M. A., Bohlken, J., & Kostev, K. (2016). Risk factors for dementia diagnosis in German primary care practices. International Psychogeriatrics, 28(07), 1059–1065. 

Garbusow, M., Schad, D. J., Sebold, M., Friedel, E., Bernhardt, N., Koch, S. P.,. . . Heinz, A. (2016). Pavlovian-to-instrumental transfer effects in the nucleus accumbens relate to relapse in alcohol dependence. Addiction Biology, 21(3), 719–731. 

Häusler, A., Sánchez, A., Gellert, P., Deeken, F., Rapp, M. A., & Nordheim, J. (2016). Perceived stress and quality of life in dementia patients and their caregiving spouses: Does dyadic coping matter? International Psychogeriatrics, 28(11), 1857–1866. 

Heinz, A., Kluge, U., & Rapp, M. A. (2016). Heritability of living in deprived neighbourhoods. Translational Psychiatry, 6(11), e941. 

Heinz, A., Voss, M., Lawrie, S. M., Mishara, A., Bauer, M., Gallinat, J.,. . . Galderisi, S. (2016). Shall we really say goodbye to first rank symptoms? European Psychiatry, 37, 8–13. 

Heinz, A., Beck, A., & Rapp, M. A. (2016). Alcohol as an Environmental Mortality Hazard. JAMA Psychiatry, 73(6), 549. 

Heinzel, S., Lorenz, R. C., Pelz, P., Heinz, A., Walter, H., Kathmann, N.,. . . Stelzel, C. (2016). Neural correlates of training and transfer effects in working memory in older adults. NeuroImage, 134, 236–249. 

Konrad, M., Bohlken, J., Rapp, M. A., & Kostev, K. (2016). Depression risk in patients with heart failure in primary care practices in Germany. International Psychogeriatrics, 28(11), 1889–1894. 

Liu, S., Schad, D. J., Kuschpel, M. S., Rapp, M. A., Heinz, A., & Allen, P. (2016). Music and Video Gaming during Breaks: Influence on Habitual versus Goal-Directed Decision Making. PLOS ONE, 11(3), e0150165. 

Sebold, M., Schad, D. J., Nebe, S., Garbusow, M., Jünger, E., Kroemer, N. B.,. . . Huys, Q. J. M. (2016). Don't Think, Just Feel the Music: Individuals with Strong Pavlovian-to-Instrumental Transfer Effects Rely Less on Model-based Reinforcement Learning. Journal of Cognitive Neuroscience, 28(7), 985–995. 

Ströhle, A., & Rapp, M. A. (2016). Prevention of Cognitive Decline: A Physical Exercise Perspective on Brain Health in the Long Run. Journal of the American Medical Directors Association, 17(5), 461–462. 


Aichberger, M. C., Heredia Montesinos, A., Bromand, Z., Yesil, R., Temur-Erman, S., Rapp, M. A.,. . . Schouler-Ocak, M. (2015). Suicide attempt rates and intervention effects in women of Turkish origin in Berlin. European Psychiatry, 30(4), 480–485. 

Aichberger, M. C., Bromand, Z., Rapp, M. A., Yesil, R., Montesinos, A. H., Temur-Erman, S.,. . . Schouler-Ocak, M. (2015). Perceived ethnic discrimination, acculturation, and psychological distress in women of Turkish origin in Germany. Social Psychiatry and Psychiatric Epidemiology, 50(11), 1691–1700. 

Bohlken, J., Schulz, M., Rapp, M. A., & Bätzing-Feigenbaum, J. (2015). Pharmacotherapy of dementia in Germany: Results from a nationwide claims database. European Neuropsychopharmacology, 25(12), 2333–2338. 

Heinz, A., Charlet, K., & Rapp, M. A. (2015). Public mental health: A call to action. World Psychiatry, 14(1), 49–50. 

Kuschpel, M. S., Liu, S., Schad, D. J., Heinzel, S., Heinz, A., & Rapp, M. A. (2015). Differential effects of wakeful rest, music and video game playing on working memory performance in the n-back task. Frontiers in Psychology, 6, 27. 

Rapp, M. A., Kluge, U., Penka, S., Vardar, A., Aichberger, M. C., Mundt, A. P.,. . . Heinz, A. (2015). When local poverty is more important than your income: Mental health in minorities in inner cities. World Psychiatry, 14(2), 249–250. 

Ströhle, A., Schmidt, D. K., Schultz, F., Fricke, N., Staden, T., Hellweg, R.,. . . Rieckmann, N. (2015). Drug and Exercise Treatment of Alzheimer Disease and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis of Effects on Cognition in Randomized Controlled Trials. The American Journal of Geriatric Psychiatry, 23(12), 1234–1249. 

Treusch, Y., Majic, T., Page, J., Gutzmann, H., Heinz, A., & Rapp, M. A. (2015). Apathy in nursing home residents with dementia: Results from a cluster-randomized controlled trial. European Psychiatry, 30(2), 251–257. 


Garbusow, M., Schad, D. J., Sommer, C., Jünger, E., Sebold, M., Friedel, E.,. . . Rapp, M. A. (2014). Pavlovian-to-Instrumental Transfer in Alcohol Dependence: A Pilot Study. Neuropsychobiology, 70(2), 111–121. 

Häusler, A. (2014). Psychosoziale Therapie bei beginnender Demenz: Das DYADEM-Unterstützungsprogramm für Menschen mit Demenz und ihre Partner. Frankfurt am Main: Mabuse-Verl.

Heinzel, S., Riemer, T. G., Schulte, S., Onken, J., Heinz, A., & Rapp, M. A. (2014). Catechol-O-methyltransferase (COMT) Genotype Affects Age-Related Changes in Plasticity in Working Memory: A Pilot Study. BioMed Research International, 2014(3), 1–7. 

Schad, D. J., Jünger, E., Sebold, M., Garbusow, M., Bernhardt, N., Javadi, A.-H.,. . . Huys, Q. J. M. (2014). Processing speed enhances model-based over model-free reinforcement learning in the presence of high working memory functioning. Frontiers in Psychology, 5(587), 518. 

Schlagenhauf, F., Huys, Q. J., Deserno, L., Rapp, M. A., Beck, A., Heinze, H.-J.,. . . Heinz, A. (2014). Striatal dysfunction during reversal learning in unmedicated schizophrenia patients. NeuroImage, 89, 171–180. 

Zaytseva, Y., Korsakova, N., Gurovich, I. Y., Heinz, A., & Rapp, M. A. (2014). Luria revisited: Complex motor phenomena in first episode schizophrenia and schizophrenia spectrum disorders. Psychiatry Research, 220(1-2), 145–151. 


Heinzel, S., Schulte, S., Onken, J., Duong, Q.-L., Riemer, T. G., Heinz, A.,. . . Rapp, M. A. (2013). Working memory training improvements and gains in non-trained cognitive tasks in young and older adults. Aging, Neuropsychology, and Cognition, 21(2), 146–173. 

Majić, T., Gutzmann, H., Heinz, A., Lang, U. E., & Rapp, M. A. (2013). Animal-Assisted Therapy and Agitation and Depression in Nursing Home Residents with Dementia: A Matched Case–Control Trial. The American Journal of Geriatric Psychiatry, 21(11), 1052–1059. 

Rapp, M. A., Mell, T., Majic, T., Treusch, Y., Nordheim, J., Niemann-Mirmehdi, M.,. . . Heinz, A. (2013). Agitation in Nursing Home Residents With Dementia (VIDEANT Trial): Effects of a Cluster-Randomized, Controlled, Guideline Implementation Trial. Journal of the American Medical Directors Association, 14(9), 690–695. 

Schlagenhauf, F., Rapp, M. A., Huys, Q. J. M., Beck, A., Wüstenberg, T., Deserno, L.,. . . Heinz, A. (2013). Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence. Human Brain Mapping, 34(6), 1490–1499. 


Bromand, Z., Temur-Erman, S., Yesil, R., Heredia Montesinos, A., Aichberger, M. C., Kleiber, D.,. . . Rapp, M. A. (2012). Mental health of Turkish women in Germany: Resilience and risk factors. European Psychiatry, 27, S17-S21. 


Krampe, R. T., Doumas, M., Lavrysen, A., & Rapp, M. A. (2010). The costs of taking it slowly: Fast and slow movement timing in older age. Psychology and Aging, 25(4), 980–990. 


Rieckmann, N. (2009). Gene-Environment Interactions and Depression. JAMA, 302(17), 1859. 


Rapp, M. A., Schnaider-Beeri, M., Grossman, H. T., Sano, M., Perl, D. P., Purohit, D. P.,. . . Haroutunian, V. (2006). Increased Hippocampal Plaques and Tangles in Patients With Alzheimer Disease With a Lifetime History of Major Depression. Archives of General Psychiatry, 63(2), 161.