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Prof. Dr. B. Hocher

Lehrstuhl Experimentelle Ernährungsmedizin

Prof. Dr. med. B. Hocher

Head of the Group

Experimental Nutritional Science

Curriculum Vitae:

Prof. Dr. med. Berthold Hocher studied medicine at the Free University of Berlin and the University of Heidelberg. He started his research career at the department of molecular biology and biochemistry at the Free University of Berlin where he also accomplished his doctoral thesis. In the following years he worked clinically in the field of internal medicine with the focus on endocrinology and nephrology. After clinical posts at the Benjamin Franklin University Hospital of the Free University of Berlin and the Charité, he became a consultant nephrologist and associated professor of internal medicine at the University Hospital Bern/Switzerland. Thereafter, he worked in the pharmaceutical industry in pre-clinical and clinical drug development (Solvay Pharmaceuticals, Hannover, Germany and Roche, Basel, Switzerland). He currently holds a full professorship at the University in Potsdam for experimental nutritional medicine and is visiting professor at the Jinan University, Guangzhou, China. The main topics of his research group are fetal programming of cardiovascular diseases, exploration of novel targets for the treatment of diabetic complications focusing on diabetic nephropathy as well as biomarker research.

Zwölf ausgewählte Artikel

 

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Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension.

Hocher B, Thöne-Reineke C, Rohmeiss P, Schmager F, Slowinski T, Burst V, Siegmund F, Quertermous T, Bauer C, Neumayer HH, Schleuning WD, Theuring F.

J Clin Invest. 1997

 

Renal endothelin system in polycystic kidney disease.

Hocher B, Zart R, Schwarz A, Vogt V, Braun C, Thöne-Reineke C, Braun N, Neumayer HH, Koppenhagen K, Bauer C, Rohmeiss P.

J Am Soc Nephrol. 1998

 

Association of maternal G protein beta3 subunit 825T allele with low birthweight.

Hocher B, Slowinski T, Stolze T, Pleschka A, Neumayer HH, Halle H.

Lancet 2000

 

CC chemokine receptor 5 and renal-transplant survival.

Fischereder M, Luckow B, Hocher B, Wüthrich RP, Rothenpieler U, Schneeberger H, Panzer U, Stahl RA, Hauser IA, Budde K, Neumayer H, Krämer BK, Land W, Schlöndorff D.

Lancet 2001

 

Relaxin is an independent risk factor predicting death in male patients with end-stage kidney disease.

Hocher B, Ziebig R, Krause R, Asmus G, Neumayer HH, Liefeldt L, Stasch JP.

Circulation 2004

 

Diabetic endothelin B receptor-deficient rats develop severe hypertension and progressive renal failure.

Pfab T, Thöne-Reineke C, Theilig F, Lange I, Witt H, Maser-Gluth C, Bader M, Stasch JP, Ruiz P, Bachmann S, Yanagisawa M, Hocher B.

J Am Soc Nephrol. 2006

 

Low birth weight, a risk factor for cardiovascular diseases in later life, is already associated with elevated fetal glycosylated hemoglobin at birth.

Pfab T, Slowinski T, Godes M, Halle H, Priem F, Hocher B.

Circulation 2006

 

Lack of endothelial nitric oxide synthase promotes endothelin-induced hypertension: lessons from endothelin-1 transgenic/endothelial nitric oxide synthase knockout mice.

Quaschning T, Voss F, Relle K, Kalk P, Vignon-Zellweger N, Pfab T, Bauer C, Theilig F, Bachmann S, Kraemer-Guth A, Wanner C, Theuring F, Galle J, Hocher B.

J Am Soc Nephrol. 2007

 

Cardio-renal effects of the A1 adenosine receptor antagonist SLV320 in patients with heart failure.

Mitrovic V, Seferovic P, Dodic S, Krotin M, Neskovic A, Dickstein K, de Voogd H, Böcker C, Ziegler D, Godes M, Nakov R, Essers H, Verboom C, Hocher B.

Circ Heart Fail. 2009

 

Endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 prevents hypertensive cardiac remodeling in a blood pressure-independent manner.

Kalk P, Sharkovska Y, Kashina E, von Websky K, Relle K, Pfab T, Alter M, Guillaume P, Provost D, Hoffmann K, Fischer Y, Hocher B.

Hypertension 2011

 

Loss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancy.

Nair AV, Hocher B, Verkaart S, van Zeeland F, Pfab T, Slowinski T, Chen YP, Schlingmann KP, Schaller A, Gallati S, Bindels RJ, Konrad M, Hoenderop JG.

Proc Natl Acad Sci U S A. 2012

 

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

Nat Genet. 2013

 

 

 

 

 

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Kontakt

Universität Potsdam
Institut für Ernährungswissenschaften

Professur Experimentelle Ernährungsmedizin

Arthur-Scheunert-Allee 114-116
14558 Nuthetal
OT Bergholz-Rehbrücke
Tel.: 033200/88-5508
Fax: 033200/88-5541
E-Mail:
hocher@uni-potsdam.de

Universität Potsdam, Mathematisch-Naturwissenschaftliche Fakultät, Institut für Ernährungswissenschaften - Experimentelle Ernährungsmedizin